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Naptumomab estafenatox : ウィキペディア英語版 | Naptumomab estafenatox
Naptumomab estafenatox (ABR-217620) is a drug being developed for the treatment of various types of cancer like non-small cell lung carcinoma and renal cell carcinoma.〔(ClinicalTrials.gov )〕 ==Mechanism of action== Chemically, it is a fusion protein consisting of the antigen-binding fragment (Fab) of a monoclonal antibody with the superantigen ''staphylococcal enterotoxin A'' (SEA/E-120, "estafenatox").〔(WHO Drug Information )〕 The Fab binds to 5T4, an antigen expressed by various tumor cells, and the superantigen induces an immune response by activating T lymphocytes.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Naptumomab estafenatox」の詳細全文を読む
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